Green Coffee Bean Extract
What Is Green Coffee Bean Extract Used for Today?
Animal studies have found evidence that chlorogenic acids from green coffee bean extract can reduce blood pressure. 1 Based on this, researchers have conducted human trials.In a double-blind, placebo-controlled study of 117 males with mild hypertension , GCBE was given for one month at 46 mg, 93 mg, or 185 mg daily. 2 After 28 days, the results showed a significant improvement in blood pressure as compared to placebo in the 93 mg and 185 mg groups. The results seen were dose-related, meaning that the greater the dose, the greater the improvement. The finding of dose-relatedness tends to increase the likelihood that a studied treatment is actually effective. Antihypertensive benefits were also seen in a much smaller study using purified chlorogenic acids. 3
GCBE has also shown a bit of promise for aiding weight loss4 , perhaps in part due to its chlorogenic acid content. 5 The caffeine in GCBE might also provide a slight weight loss benefit.
GCBE products are sometimes said to help prevent diabetes; however, this claim derives only from weak evidence involving consumption of ordinary coffee, 6 and cannot be relied upon at all.
Roasted (as opposed to green) coffee beans contain the substances kahweol and cafestol, which appear to increase levels of LDL ("bad" cholesterol). 7 The fact that GCBE does not contain these substances is used as an argument in its favor. However, these substances remain in the coffee grounds and so they are also not present in standard beverage coffee, so this is probably not a significant point. (Unfiltered or boiled coffee, with the grounds left in, however, may present a risk.)
Dosage
In the large human trial of GCBE for hypertension noted above, the extract was most effective when taken at a dose of 185 mg daily.Since green coffee bean extract typically contains about 30% chlorogenic acids, this works out to a dose of about 60 mg of chlorogenic acids daily. Another study used 140 mg of purified chlorogenic acids daily.
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Safety Issues
GCBE is thought to be a safe substance. In human trials, no significant adverse effects have been seen.In theory, the caffeine content of GCBE could potentially cause problems for some people. However, since GCBE contains only about 10% caffeine by weight, a high daily dose contains no more than about 20% of the caffeine content of a strong cup of coffee.
Maximum safe doses in pregnant or nursing women, young children, or people with liver or kidney disease have not been established.
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